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Post by Tiggerwoos on Mar 15, 2006 22:02:16 GMT
As many of you will have heard, the news of today has 6 young previously healthy UK men on life support machines after within minutes of taking a new anti-inflammatory drug on trial for rheumatoid arthritis and leukaemia left them swelling uncontrollably, with multiple organ failiure and on life support machines for what doctors say could be 6 -12 months. The individuals concerned were paid £2000 to take part in the trials, a big price to pay for what could be their lives. Doctors are unsure what to do with these victims as of course they don't know what they are dealing with and say the reaction could get worse. This to me is fuel in the fire as far as animal rights experts are concerned as it has just proved how unreliable animal testing is when it comes to human drugs, as all they could claim was that for 4 years animals had no adverse reaction to the drug, so they assumed that humans would be ok with it. This just shows how wrong this statement is, and that other methods need to be looked into, banning animal testing on drugs completely, as how long till the next human adverse reaction, its obvious, seeing as we are a completely different species. I'm hoping, although doubtful that this will make governments and the medical fields look in to withdrawing animal testing altogether and looking at safer alternative methods for the sake of the animals and so this doesn't happen again. The full story can be found in the link below for more info. channels.aolsvc.co.uk/news/article.adp?id=20060315072809990011&n=rotator&p=Platinum&c=welcome_screen
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Post by bobbywomble on Mar 16, 2006 20:01:29 GMT
what a bunch of plonkers
who in there right mind would say oh oh oh 2 grand if you inject me with a drug that might kill me or make me suffer for the rest of my life i mean honestly i have no sympathy they should be made to pay that 2 grand as a token of the cost of treatment and why is the nhs picking up the tab why has the drug company not been forced to put them into a private hospital
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Post by tabitha on Mar 17, 2006 20:19:24 GMT
This is so horrendous, I dont even know what to say. I agree with Bobbywomble that two grand is a small price to put on your life, but I still have great sympathy for these men. This wont go in the animals favour though. Even though it is obvious to us that the animal testing yet again did no good, the powers that be will still say that there need to be more testing. Plonkers is the polite way of expressing what I feel about them. If any of you know me you probably know the real word I am thinking now. My heart goes out to the animals and the families of these deluded men.
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Post by bunny on Mar 18, 2006 19:25:20 GMT
I was signed up to be a phizer tester when I was a poor student. I never actually did it, but I was sent out a lot of the information packs for several of the trials. They basically give you all the details of the drug so far, tell you that you could suffer an adverse reaction and then you have to sign a disclaimer. They do say in their packs that you will be given compensation if anything goes wrong, but when I read everything, none of it seemed worth the risks. I do feel sorry for the men involved though . I agree with Tabitha though - I don't think they will stop animal testing for this .
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Fauxmage
EV Friend
I eat food.
Posts: 186
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Post by Fauxmage on Mar 19, 2006 6:10:01 GMT
That's what I find disturbing about testing on humans, that they offer financial incentives to poor, desperate people. Why not just use prisoners, lifers who are in for murder? They can still be given a choice, I'm not suggesting they be forced. They also better start improving their computer models for drug testing too, and start phasing out animals entirely. I think that the main reason they use animals in testing isn't to find cures for humans anyway. Its to make sure they don't kill off their customers before they have made enough profit off their illnesses, and to protect against lawsuits, another threat to their profits. They don't want to cure diseases and put themselves out of work, do they?
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Rainbow
Newbie
Fish Feel Pain, Fruit Doesn't!
Posts: 23
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Post by Rainbow on Mar 25, 2006 14:43:35 GMT
Many tests can and should be done before inflicting drugs upon humans, but none of these tests need or should involve non-human animals. Given the power to test drugs on prisoners, I am scared that this power in time would be abused in some way, by somebody. Surely prisoners (whether they had been convicted of multiple murder and were destined for a life behind bars or not) would be at risk from extra tablets being slipped to prison officers.
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Post by bobbywomble on Mar 27, 2006 20:26:09 GMT
i like the idea of prisoners being used as test subjects they have no rights and are no longer needed why not make life as difficult as we can for them and have proper justice for once
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Post by peaceandglitter on Mar 28, 2006 20:04:30 GMT
Hopefully it will show the public how unreliable animal testing is. Most people just trot out the usual 'but its necesary' arguement without even realising how unreliable animal testing is, or bothering to find out about other methods And I completely agree that it would be better to test on humans who are in life imprisonment than innocent animals.
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Post by bobbywomble on Apr 3, 2006 8:53:46 GMT
yeah they should do it to lifers (or chavs)
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Post by Tiggerwoos on Apr 17, 2006 11:52:57 GMT
More news on the story. Can't say I have too much sympathy for these people anyway, but makes interesting reading. smh.com.au/news/world/man-to-...126001748.htmlApril 16, 2006 - 5:24PM A 20-year-old man who suffered severe reactions during a drug trial told a British Sunday tabloid that he wouldlose parts of his fingers and toes. Ryan Wilson, from London, and five other healthy volunteers took part in a clinical trial last month for TGN1412, a drug being tested for treatment of leukaemia and auto-immune and inflammatory diseases. "I'm definitely going to lose bits of my fingers and toes. And they say I could be in here for another six months," he told the News of the World. "I'm told it's like frostbite and my fingers will just fall off," he was quoted as saying. Large parts of his hands and feet have turned black, where flesh has died, pictures published in the newspaper reveal. Mr Wilson and the five others were each paid £2200 ($5300) for taking part in the trial, but suffered convulsions and organ failure minutes after being administered the test drug. All the other volunteers have been released from hospital. "I had heart failure, kidney failure, pneumonia, septicemia and liver failure and was ventilated on 99 per cent oxygen," he told the newspaper. The student, who said doctors told him that he defied their expectations by surviving, plans to sue the drug makers TeGenero AG of Wuerzburg, Germany, as well as Parexel International, based in Waltham, Massachusetts, which conducted the trials. In an interim report, investigators said they found no evidence of product contamination nor the use of improper practices in the trial. Britain's Medicines and Healthcare products Regulatory Agency are continuing their investigation, and have named a panel of experts to make recommendations on how drugs like this can be safely developed in the future. TeGenero initially said there had been no "drug-related adverse events" in tests on animals, but later acknowledged the drug had left monkeys with swollen glands. About 350 similar phase-one clinical trials on humans are conducted every year in Britain - tests which will continue pending further investigation.
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Post by fezzarooooo on Apr 17, 2006 11:55:16 GMT
Eugh it showed his photograph in the paper yesterday, his toes and fingers are all black & more than a tad minging looking!
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